报告主题：仿生材料对抗生物膜(Biomimetic Materials to Combat Biofilms)

报告时间：2024年8月03日（星期六），15:00-16:00

地点：创新港2-3F-033（力行楼）

报告人：Prof. Jinju (Vicky) Chen

来访单位：Loughborough University

Abstract:

Biomimetic Materials to Combat Biofilms

Biofilms pose a global threat in healthcare, industry, and the environment. Traditional methods using immobilized antimicrobials like antibiotics lead to resistance. Physical approaches like nanostructures offer temporary solutions as bacteria spread. Our multiscale surfaces delay biofilm formation but lack long-term efficacy. Lubricant-impregnated surfaces (LIS) are promising due to their slippery nature, but lubricant loss hinders their practicality. We present a novel anti-biofilm strategy: a liquid-like nanocoating that eliminates lubricant loss, potentially offering a long-lasting and sustainable solution for biofilm prevention.

摘要： 仿生材料对抗生物膜

生物膜在医疗、工业和环境领域构成全球性威胁。传统的固定抗菌剂（例如抗生素）会导抗药性。纳米结构等物理方法随着细菌的蔓延只能提供临时解决方案。我们研发的多尺度表面可以延缓生物膜的形成，但缺乏长效功效。润滑剂浸渍表面(LIS)因其润滑特性而备受关注，但润滑剂的损失阻碍了其实用性。我们提出了一种新型的抗生物膜策略：一种准液态纳米涂层，可以消除润滑剂损失，有可能为生物膜预防提供持久和可持续的解决方案。

Short Biography:

Short Bio:

Prof. Jinju (Vicky) Chen is Chair in Advanced Materials & Biointerfaces at Loughborough University. Her passion lies in tackling fundamental scientific questions at the intersection of cells and materials. This knowledge is then translated into innovative materials designs, aiming to accelerate breakthroughs in human disease treatment and biofilm control. Prof. Chen has secured £9.35 million in funding from various sources. Her research has garnered significant recognition, evidenced by her publication of 83 peer-reviewed journal papers and 85 invited talks.

She serves Loughborough in key roles such as Departmental Research Director and University Senate Member. She is Fellow of Royal Microscope Society and Member of UK Research and Innovation Talent Panel College.

https://www.lboro.ac.uk/departments/materials/staff/jinju-chen/

E-mail:j.chen4@lboro.ac.uk

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